SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f5833d826a592c78539171c7fbbcfc663ab5a6cc3cb1a79fa8f267f4f6cefdb' 
  AND token = 'KMTw0UK5afr54JpYBf28XdA3WJceSgmFWGMOFtX1YJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}