SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6e921d2c4ff6b07ae0f0cd5455121a7bb65efda10e3924446ce8927a4a3bfd' 
  AND token = 'FzM+sn5V81ItX5DOtF3u3FWkxesEiFdl47tXZt6eVbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}