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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66126e4d1213b55f3d8b43a9f07afebaf58ee43b34003a1b0e56e6b5204740d' 
  AND token = 'SU75mqFlnM7gYoOBCGESXPFfl73sIVqGKbE6cqn+uxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}