SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90d45a4519c951d717d8391f1c986fcd3074a5ee1b10ac794edfedbb3411da84' 
  AND token = '5XIwiuPhTAspzBiDKJ/44Inp2LEYTyrKgYSux9Qyri0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}