SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b9978f5c1a45c59398715ebdc0707f81a13dcbca3d6db30866a97804b6506fc' 
  AND token = 'eBanX3/lC+0UAg3X8pFifNGUcR/5D1hqRQJOHO3ewq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}