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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d01bcc61f994cf3f7d78cc1450bfcb7d0805dcbb84640026dd5779605a6850' 
  AND token = 'u3pAfBGOUE/44PE9eSHAoTd10nyWtL1WjSikRVSmm10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}