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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7436e5a844ba1e44b89171acf361f9a4b3b44f3e93a95a4393e86cb4fa14315' 
  AND token = 'VKG8wd2NRqSFCqLEO/sgVhsmny4hpgMaXcQKfn5IM0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}