SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb4868c93402a835463aa7486480c6c3addeb775d758e85dde43e79e9027698d' 
  AND token = 'lXBaDg3Y3//H+d0UQNWoRqrcr874TuQ3hr+SnnyNFvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}