SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764ff1dc39344a51c25fcaec54dcfa8a95e4108efa0d0d52a55a26c5ade49230' 
  AND token = 'HOvlHI43U7c/MMOIodMyPSduQCX3jNLILsZvD3yx9zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}