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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8cd5426fd56b8f4f0f8de335fa78785534d5197ef1a1b4d4d51e0d64619051c' 
  AND token = '97XYfLYc3LLzXpBzbOgZyfcHT2oN4V2Gu5RqwpNK4Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}