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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '107ccd61aee177c15be579611e914b14d7e6b41cb4aaf487ad80de6b5a676005' 
  AND token = 'a0jkvYHj04pnFmHb5klvWsArrG+PF1BH+sjcQd5ACVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}