SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e13aa3e616d48499699bef9419bad1e7a570522598363b35a8a2a3c956b21c78' 
  AND token = 'eCqNhfggAoAIyycw1qvcRLkKTTCwCzcbkYvMCoJ6Z1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}