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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df608b3d557ceb69b3ffe3ef0ae6160d9be75e0a766d1add27f7755cf9e201b1' 
  AND token = 'xZgbtuUyGYxyfuEDbIViAiRkRPHsvoKml7gySKzehtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}