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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c9e334dc766a6680bc536fe3a9224a4b74f3c9e8bd094973ea1f22b9b069381' 
  AND token = 'cmrw02Mg2Dtj4SUYQXGF6P4E0EAtaTPuOl9gsGseFU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}