SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d5d947ea1b2a32b81170b2693a1b0d94ac8708051accaf6010b048a2ab3ca78' 
  AND token = 'GW17/0aDt/tRC5jXoo7Qpa7U7Xv5WPt04NXgGKrNsLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}