SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f5c10bc48e56606d5ade93800bac4bef095e6682e217e0b5bf7e1e17ca10cd4' 
  AND token = 'UbDpSjsdyDltJjM5jLH+BhGqooRoNlGPmUSgE91FRUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}