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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72afc740b5fb0f15a76e6cc3c470c6ade16a3087bec42d9c9e6aa127ac087c76' 
  AND token = '/+TvYG562M+Fz8WCtxpomR0k5eT7ZHuJwzVuOWOi2kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00094

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}