SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb739b9b275f52665200ae2007a6af1b6875c2a80591c18e67708897f27ca68' 
  AND token = 'gEqTzmIiphP+I4lnYBU6qfVX0c2V7oQy3WFNc7MysmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}