SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b09a758fa6eb583c8e1456082bf080d16fb4975943a4a88ccc3f2b34dede93d' 
  AND token = 'U7lJWkgD4JOTY9pwgTMeDTZN4K1dK8UDOF4rj7ZQIJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}