SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43dbbb86a957b6955b9e9f3872a525f5c514024a374b43fb63db17122879188e' 
  AND token = 'WJZSU+RNCTociEEkmDJafSAmFZNQQSr7QR/ExDlrjU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}