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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b1e8066558afe5642c5307737487e05c687ac4990dbc4209dace32131395e3' 
  AND token = '3FfUhqbzERGYMUFNWareTWJO36aY/OMSPB6yoL7v7p8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}