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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a2b1552b6eff0d9e3650d25855541940fd94291a7aae046e2f4c19ab931c35' 
  AND token = 'gZPhMNNluiROUtX3tcwFzkJLQDYyFEkcvPtsXUXQwaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}