SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78000896bee5b24471b4eefff2617948643d1116b865f2ffa0ac644f1f4f94f' 
  AND token = 'KzoMqWEQN3am02yc7KL0vh+mNBpDCAUO7+SNfTRSF40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}