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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f688d778ad039ac85dd1c6ffb07cac7d0ec7f9d425aa24de987048259d0cfd52' 
  AND token = 'JoHWCMTrlBYfRliTvyohZyhLogiGFB51+myDuk1xEL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}