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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a36a1a8b7499f6b44377c24bb3f881ea2081a85f978463711ab801a91828348' 
  AND token = 'LMN+gATZXsceFMm8Sg3Amrj4wm6NC8hcydP/INDte4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}