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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57a8eb1bd6ba1470996db1166d77a4ccbb297a8ed22228cebfc8963b26c6244b' 
  AND token = 'ed2GgMhjnnrhxnrYDPASuXU/8XHHjkF4xsMWt2p3DY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}