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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a78e2176e68f8f1c9b3346834efe2af4f367825bc986b07a987bf2063c558207' 
  AND token = 'CHOcFQBeYzu8KHhy65zosX+YCdiw4bD2QEbc2EAZkio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}