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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b2509847809bc468c453320a3f4d96d34d9cea7e84fbf75f80cdd4e5ea7ca81' 
  AND token = 'mHVPSqDJWMRKhN8yGHYQBqnLkIqOtN1B2Mz4F8EaRLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}