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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fc7cb38221eb093e812ea6b7907b7c4d64a90e94be060ce91e2b7b71041791' 
  AND token = '8PI9Wzys+rl8WNM7fHWAy+/q4SGwFrKgtOTwWSoQXPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}