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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bf768582ac7b6012f280de719f48edd85f5c11fdc3265c7a195ed8153e02c29' 
  AND token = '/QpIuXSNSI7RaUkdGyHugcC1q+rDjxkT7ZHFXkD79fA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}