SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d34398719a4d731c8e65b9299bab767a42a0a0ea7734abb3416b37c25d72ab3' 
  AND token = 'nrhqx+Hw7Ja8yacSlpaJ/LJuXc+urYjoSedUBbujOAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}