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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef1035861818fe9c60a960ab81a7fd6a77ddb27b5acd352c6d4bccbfa6e559c' 
  AND token = '2VxDAUqCAWIgQkZkJLO22nA0DR3aZiZPtJgkUrBPJ8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}