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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef5a69d1f8888cbb018d797e5d0051d393595b7a6fc50a04de73b424c4b8d240' 
  AND token = 's1iRgxQEC7xInGvawR2fHuzfAdsQ8zwNZyWNTBdAzxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}