SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae1ab102e2d12bea2e656f43080ce547f571270215c25ecf401a05439d19c7b' 
  AND token = 'JRAF+QjwLxnc0YXA0s3AEc/9f1o6sbmyigROXbfPXwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}