SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58f91ec860be229b9ea0aa7df3ff45b9149786be50693a24d737a2597a33a346' 
  AND token = 'uTD/OqIyLVqKskulkuH9qmfd3ERIFtLUURAdqaZZ4GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}