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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ac4330b0523429f9744ec6d4170a247fe29a092504b712f74bace40d137b9c' 
  AND token = 'hR9L8lKUAU8147lq2+nR/tQ+RTagXbJUOsQhb8uo2EI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}