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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed5dd4d88166d09e4224b6ded0da6ec2224bd6f28ff87c5fd0e5cf4e05d45c5' 
  AND token = 'wk4we2/7Nv+8/SIubZYaPIOZQnxpZ0XvDfzIcsEkctY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}