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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8aa8a9b27c2293be9113898bda9ce1a2b00ca13d25d0535128e02502b669e3' 
  AND token = 'pF+1q56K1jUxG81zTd+yIb2ARL7JDkcYxq5wU/AOPKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}