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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f65435e5d680d5a4ceb7170e9d3ab50bda8c47532d7bf0cfadf91b96f19bd995' 
  AND token = 'shQ5d+Nodh5KLv58QB7SUkCWhfb9CF3guLIOe+yFlJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}