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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b158cfeab22e27b5703fb6d606d14cc22f2e86c2a85d5f597b256ef840c363' 
  AND token = 'IJYWt6CSiTiw1DOytQliWfAVLEuOgxIRb1GDK9y4h5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}