SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06016233ee71fa7bff2080a34dec5fee3b4f2ddada74ce121ca6c5d0ed872191' 
  AND token = 'yefogGmYNAYHF8I5xhL+kxb9nCN8qm4zR/Y0e9XU9G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}