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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a8a08988d5fd6abe4f0ac223e30bf971ea8797fb9af51424d7d3646c1f937ff' 
  AND token = 'Pncg+vaeCij4Fg5OtqbfUeB+5TYnqLJGf0DIcTJSTjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}