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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3938962efd05b80e6026c847ae5a8516cad5a2c3b801be2c5be20aeaf1158e' 
  AND token = 'Ed1P9Y0Xt2SbtAb4JcaLZspbNt7AHB7r6bFsP/ahqNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}