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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfd728d3c31577caea30bffbb05be6fb9dbc264a0a061183c56174f5955d2265' 
  AND token = '1nH0DyfkirbyOdzQrbzyo3E8VP3YmW9V+zQXqvM21Zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}