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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d2389b14e802883c31cc3e247c337e6d5ce2d6ad3470f3d1977ec58bd0f2ac' 
  AND token = '6TAe/GWuPbB1LM34/iE+E38kWEWqNW5ceRwt53fAgK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}