SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f48dcc17d13b437be4da22262749d0c40f2332d9bf309360604008e2feb148' 
  AND token = 'VKL/3vVTRrj4Stju2jHjBnXD4VB40cONN4LNeQcQYJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}