SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c43d4f1aed83c39b78233ea1e75ef807554452ad19649c0f38fdf9ebb7c62e1' 
  AND token = 'TAILKr0VIlAWvK0rueJZo5CkGcY6KwkTWtR3LI8c+s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}