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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4290abd40793c458712721e84b5909e0e3b042993529482a206196a6440a4b3' 
  AND token = 'Dl7l2ALH/ISDO7NXQzSdc7bcECI8oJktUyyjKTTgzlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}