SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50a6629be16aec5a0319a51bd27c6c8e51c461fc455c8471416733d5a0472c3' 
  AND token = '3oProABJXTjZ38fucx4YkIG0MGuPr4AF3OdIMuHudmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}