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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe46be0b56a962dea432e0f705f9b9c7a8227f93c51a7148f7348a367946d5de' 
  AND token = 'oL8ZJfLpD4fD9QIXbO+VrdxBAt5riBaIblWzcPqnPVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}